Doctored: Fraud, Arrogance, and the Tragedy of Alzheimer’s

Recommended on: 29th July 2025

Doctored: Fraud, Arrogance, and the Tragedy of Alzheimer’s

A sobering must-read on science gone wrong

If you’ve ever wondered why, after decades of research and billions of dollars, we still don’t have a truly effective treatment for Alzheimer’s, Doctored: Fraud, Arrogance, and the Tragedy of Alzheimer’s offers an unsettling but essential explanation.

Charles Piller—a top-notch investigative journalist—walks us through how a shaky idea (the “amyloid hypothesis”) came to dominate Alzheimer’s research for over 20 years. But the real kicker? Some of the most-cited studies backing that idea appear to be fraudulent. We’re not talking honest mistakes here—think digitally altered images, data manipulation, and institutional indifference on a scale that’s hard to believe… until you see the receipts.

Piller doesn’t write with malice—he writes with care. And what makes this book so important is that it lays bare not just the scientific misconduct, but also the real-world consequences: promising research avenues shut down, funding funneled in the wrong directions, and families left hoping for treatments that were built on sand.

This isn’t a feel-good read—but it’s an urgently necessary one. If we want better science—and in this case, better hope for those affected by Alzheimer’s—we have to be willing to look squarely at what’s gone wrong.

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